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Since the days of Leeuwenhoek in the seventeenth century, microscopy has been two-dimensional. This may well be changed by the innovation of parallel Optical low-Coherence Tomography by Heliotis Inc. Very much like in nature the “smart pixel”-technology imitates what happens with photons in the eye: every sensor (pixel in our case) checks the incoming data and reduces it to the amount needed for generating a suitable image. The “smart pixel”-technology principally does the same but at a very high dynamic level. The pOCT technology therefore offers a literally “smart” way of generating 3D images through microscopes, thus bringing conventional 2D microscopy to unprecedented heights.

The OCT principle is similar to ultrasonic imaging, but uses light instead of acoustic waves. The sample under investigation is illuminated by a low-coherence light source. The light reflected from the sample is combined with a reference signal, leading to an interferometric signal that is further processed to yield depth information. Heliotis’s new approach is based on a dedicated CMOS 2D-array sensor where every single pixel can acquire and process the optical signal in parallel (so-called “smart pixel” technology). Each pixel of the image sensor features an electronic circuit that performs real-time image pre-processing. A single sweep of the reference mirror therefore allows a scan through the complete sample and yields a full 3D tomographic or topographic image (depending on the penetration depth of the light).  

For details, please contact info@heliotis.ch

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